[403] A Survey of Practice Patterns of Participants in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology (NGC)

Ann T Moriarty, Ritu Nayar, Manon Auger, Daniel FI Kurtycz, Nicole Thomas, Rodolfo Laucirica, Vijayalakshmi Padmanabhan, Rhona Souers, Mary R Schwartz, Mostafa Fraig. AmeriPath Indiana, Indianapolis, IN; Northwestern University Feinberg School of Medicine, Chicago, IL; McGill University Health Center, Montreal, Canada; University of Wisconsin, Wisconsin State Lab of Hygeine, Madison, WI; College of American Pathologists, Northfield, IL; Baylor College of Medicine, Houston, TX; Dartmouth-Hitchcock Medical Center, Lebanon, NH; Methodist Hospital, Houston, TX; University of Louisville, Louisville, KY

Background: Nongynecological cytology(NGC) practices are expected to expand relative to gynecologic cytology.
Design: The Supplemental Questionnaire: Current Nongynecologic(Non- FNA) Practices in Cytopathology Laboratories(NGSQC) mailed to 2059 laboratories in 2010.
Results: 51% of laboratories responded(1048/2059) where NGC samples were reviewed in non-profit non-training settings by pathologists without specialty training. Cytotechnologists reviewed NGC in 67.4%(675/1002) of laboratories. Annual mean and median volumes of NGC were 1,927 and 858. Laboratories use more than one method to process NGC; cell-blocks are most frequent(930/1029; 90.4%) and are created with centrifugation to pellet (56%;538/961). Direct smears are second most frequent. Discrete staining is preferred to batch staining.

Specimens Preparatory Methods
SpecimenN% of LaboratoriesMethods (%)
   SmearCytocentrifugationSurePathThinPrepCell Block
Body Fluid99295.850.756.57.551.888.8
Bronchoalveolar lavage90087.047.749.26.952.067.4

indicates specimen types and methods used in 1035 reporting laboratories. NGC is used for molecular studies in 34.9%(350/972) of laboratories; flow cytometric immunophenotyping is performed by 55.9%(554/991) and immunocytochemistry(ICC) by 92%(911/991) of responding laboratories. Specimen completion (TAT) is two days or less. Cyto-histological correlation is done by most laboratories concurrently and retrospectively.
Conclusions: The results of this 2010 survey can serve as a basis for future efforts in quality assurance and process improvement in NGC.
Category: Cytopathology

Tuesday, March 5, 2013 1:00 PM

Poster Session IV # 104, Tuesday Afternoon


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