Validation of Whole Slide Scanning for Use in Real-Time Clinical Frozen Section Consultation
Scott H Bradshaw, Eric Belanger, Manisha Lamba, Kien T Mai, Susan J Robertson, Harman Sekhon. Ottawa Hospital, Ottawa, ON, Canada
Background: Digital slide scanning offers the posibility for a tertiary care hospital to provide an intra-operative consultation service to satellite hospitals without requiring a staff pathologist to be physically present at the satellite hospital. Before such a service could be offered, however, slide scanning would need to be validated to ensure that the additional step does not introduce error in diagnosis or unacceptable delay. The goal of this study is to assess diagnostic accuracy on digital vs glass slides.
Design: 42 frozen section cases selected to represent the range of specimens requiring intra-operative consultation at our institution were digitally scanned. The specimens were chosen with bias toward difficult consults to increase the chance of uncovering potential issues with the slide scanning process. The digital and glass slides were reviewed by four pathologists, with a 30 day washout period between reviews. The distribution of cases is summarized in table 1.
|Bx, R/O malignancy||3|