[1008] Revisiting Decreasing Sperm Density in USA: A Single Center Experience

Muhammad Rasul, Nicole Rosa, Sakib Rasul, Pavan Kumar, Humayun Islam, Fred Moy. Westchester Medical Center, Valhalla, NY; New York Medical College, Valhalla, NY

Background: The potentially harmful environmental impact on male reproductive capacity has been identified as a public health issue of increasing concern. However, little attention has been paid to advertised warnings, possibly because the warnings were based on data from selected groups of men recruited from infertility clinics, semen donors, and/or candidates for vasectomy. This retrospective review done at our institution from 2001 to 2011 indicates that the mean sperm density has decreased significantly over the last decade.
Design: We conducted a broad search of major electronic databases and paper documentation from within our institution. We systematically reviewed all the cases in our hospital since 2001 and statistical analysis was performed using SPSS. The major methodological problem of this analysis is that data was collected exclusively from our own patient population alone without a comparable control group.
Results: In our study from 2001 to 2011, a total of 709 patients were included. Mean sperm density decreased (∼ 50%) from 2001 to 2011. There was a particularly sharp decline of mean sperm density from 2004 to 2005 (282 to 48 x 106). Our finding is concordant with meta-analysis of National data of USA. No changes were noted in mean Volume, PH, morphology, or motility of sperm.
Descriptive analysis: Sperm Density

Conclusions: Our study supports the current hypothesis of decline in sperm density in USA over the last decade. Similar studies with external control validation is essential for further confirmation as well as subsequent etiologic analysis, as the overall impact of semen analysis on target population is enormous in terms of level of intervention, and associated emotional and financial burden.
Category: Genitourinary (including renal tumors)

Wednesday, March 6, 2013 1:00 PM

Poster Session VI # 158, Wednesday Afternoon


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