Atypia in Papillary Lesions of Breast in Fine Needle Aspiration Biopsy and Association with Malignancy
Rashmi Batra, Rajesh Singla, Hillary Pearson, Jean Marc Cohen, Manju Harshan. Beth Israel Medical Center, New York, NY
Background: Fine needle aspiration biopsy(FNAB) is a frequiently used method for diagnosing papillary lesions of the breast. The challenge is in differentiating papillomas from benign non papillary proliferations and to distinguish benign papillomas from malignancy which includes papillary and non papillary types.
Design: The pathology database of Beth Israel medical center was searched for women who under went excisional biopsy after an initial diagnosis of papillary lesion(PL) on FNAB. 130 cases were identified. The biopsies were done with and with out ultrasouind guidance.Ages ranged from 20 to 92. The findings were categorised on the basis of presence or absence of atypia on FNAB and the final diagnosis.
Results are shown in the tables.
|Diagnosis on excisonal biopsy||PL with atypia on FNAB n (%)||PL without atypia on FNAB n (%)|
|Carcinoma( IDCA, DCIS, Papillary) n=28||12 (9.2%)||16 (12.3%)|
|LCIS n=7||3 (2.3%)||4 (3%)|
|Papilloma with atypia n=6||4 (3%)||2 (1.5%)|
|Papilloma n=63||8 (6.1%)||55 (42.3%)|
|FCC/FA/BPT n=25||0 (0%)||25 (19.2%)|
|Adenomyoepithelioma n=1||0 (0%)||1 (0.7%)|