[335] Distribution of the Bethesda System-Thyroid Diagnostic Categories in the African-American Population in Conjunction with Surgical Pathology Follow-Up.

Pamela A Archuletta, Raja M Gidwani, Opada Alzohaili, Julie Samantray, Sudeshna Bandyopadhyay, Jining Feng, Dongping Shi, Paul Tranchida, Mujtaba Husain, Vinod Shidham, Tamar Giorgadze. Wayne State University, Detroit, MI

Background: African Americans (AA) have a higher incidence of malignancy compared to Caucasians in the US. However, a recent report indicates that the incidence of thyroid malignancy in AA is half that of Caucasians. The aim of this study is to assess the distribution of malignant versus benign thyroid disease in AA in an urban based academic hospital setting. Our study looks at the AA population compared to other racial groups with respect to FNA of thyroid lesions in correlation with final surgical pathology.
Design: We retrospectively reviewed thyroid FNA cytology between January 2005 and August 2010. Consecutive FNA specimens with corresponding follow-up surgical pathology were included. The patients were categorized as (AA) and Non African Americans (NAA) which included Caucasians (C), Hispanics (H), and "Others" (O). The FNA results were classified using the latest edition of the Bethesda System for Reporting Thyroid Cytopathology (TBS-Thy) and the follow-up surgical pathology were used for final categorization.
Results: 238 patients met our inclusion criteria- 139 AA (58%), 99 NAA [36 C (15%), 3 H (1%), 63 O (26%)]. The average age for AA was 51 (range 20-88) and for NAA was 53 (range 25-86) years. There were more females than males in the AA versus the NAA group (83% versus 74%). The incidence of thyroid lesions in FNA specimens was similar between these two populations (Table 1). The distribution of benign versus malignant diagnoses on follow-up surgical pathology were correlated with TBS-Thy class as summarized in Figure 1.

Table 1
RaceAge (Mean)IIIIIIIVVVI
AA537%57%19%2%2%13%
NAA497%50%18%13%<1%12%





Conclusions: Our data suggest that distribution of benign versus malignant lesion in thyroid FNA with surgical pathology follow-up is similar for TBS-Thy classes I-III, V, and VI in AA versus NAA. There was a difference noted in class IV between the two groups, but the small sample size precludes addressing the difference noted.
Category: Cytopathology

Monday, February 28, 2011 9:30 AM

Poster Session I Stowell-Orbison/Surgical Pathology/Autopsy Awards Poster Session # 47, Monday Morning

 

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