The Role of Postoperative Radiotherapy in the Management of Parotid Pleomorphic Salivary Adenomas: Is There Any Benefit?
Manal Atwan, Lorna Cooper. Glasgow Royal Infirmary, University of Glasgow, Scotland, United Kingdom
Background: Introduction: Pleomorphic Salivary Adenoma is the most common tumour of the Parotid Gland. Currently no national management guidelines exist. The objective of this study was to evaluate the role of adjuvant radiotherapy.
Design: A retrospective study of all patients with a histological diagnosis of PSA between 1981 and 2008 in Greater Glasgow and Clyde was undertaken. From intra- operative notes and pathology reports, adherence to facial nerve, excision margins, capsule status and postoperative radiotherapy were analysed. Two cohort groups were identified. The first cohort underwent surgery alone while the second received postoperative radiotherapy. Post-operative recurrence, short and long- term complications were compared in the two groups.
Results: 201 patients were identified. 167 (83%) had surgery alone and 34(17%) received adjuvant radiotherapy. Medical notes were retrievable in all patients receiving postoperative radiotherapy and in only 58 surgical patients .The rate of recurrence was 1.7% (1/58) in surgical patients and 2.9% (1/ 34) in patients receiving adjuvant radiotherapy. Short -term complications were significantly higher in the second cohort accounting for 100% compared to 38% in the first. While long- term complications 15/58 (25%) and 12/34 (32%) were observed in the first and second cohort respectively.
Conclusions: There was no significant difference in the recurrence rate between the two groups. Short term and long term complications were significantly higher in the postoperative radiotherapy cohort. Adjuvant radiotherapy is therefore not recommended in the treatment of PSA. As well as a higher long term complication rate, radiotherapy is less cost effective.
Category: Head & Neck
Wednesday, March 2, 2011 9:30 AM
Poster Session V # 149, Wednesday Morning