Diagnostic Accuracy of Core Needle Biopsy of Bone Lesions: Analysis of 230 Cases
G Gonlusen, E Calis, M Ergin, S Erdogan, C Ozkan. Cukurova University Medical Faculty, Adana, Turkey
Background: Core needle biopsy has many advantages in the treatment of bone tumors. The accurate diagnosis of bone tumors is important for successful treatment. The aim of this study is to assess the diagnostic value of fluoroscopy-guided core needle biopsy in the bone lesions.
Design: Between 2004-2009, 230 bone biopsies were performed by Jamshidi needle. The diagnoses of these biopsies were compared with final diagnoses of open biopsy and/or definitive operation.
Results: One hundred eighty eight specimens (81.7%) were determined to be adequate for histologic diagnosis. An experienced pathologist on bone pathology evaluated all cases. One hundred and seven cases were evaluated as benign, 81 cases were malign. Osteosarcoma and giant cell tumor were the most common tumors of malignant and benign cases respectively. In our series the overall sensitivity was 98.4% and specifity was 96.2%. There were one false-positive and three false-negative diagnoses. The positive predictive value of core needle biopsy was 99.4 %.
Conclusions: The results indicate that needle biopsy in bone lesions is safe, easy to perform, requires small amount of tissue and permit high diagnostic accuracy.
Category: Bone & Soft Tissue
Tuesday, March 23, 2010 9:30 AM
Poster Session III # 29, Tuesday Morning