Conticabase: A Shared European Database and Virtual Tumor Bank Dedicated to Soft Tissue and Visceral Mesenchymal Tumors. A Project from CONTICANET Network of Excellence
JM Coindre, T Gaudin, D Meunier, JB Courreges, V Brouste, S Baconnier, JY Blay. Institut Bergonié, Bordeaux, France; Centre Léon Bérard, Lyon, France
Background: Sarcomas are rare and heterogeneous with the need of developing joint research programmes based on common shared tumour banks. One main objective of CONTICANET, a European network of excellence with 12 clinical sarcomas Centers, is to set up a network wide, shared information system via Internet.
Design: Analysis of a questionnaire which has been circulated among partners has shown that main objectives of the database should be knowledge of tissue availability in order to initiate collaborative biologic / genomic studies and knowledge of histological, clinical, therapeutic and follow-up data in order to initiate pathological and prognostic studies; and that potential barriers could be difficulty to share data, to merge retrospective data and to collect prospective data. Users requirements were defined accordingly. The software has been developed with java and the database server is MySQL. The project has been designed according to current software engineering methodology using open source tools.
Results: Conticabase is now available (www.conticabase.org) with the following characteristics: security of the system with different rights of access, track for any access and change of data; description of data on primary tumour (clinical, pathology, treatment), follow-up, samples with paraffin embedded tissue and frozen tissue, molecular biology characteristics; possibility of import and export data from / to standard formats; query tool allowing to know the number and the list of patients corresponding to a defined category; possibility to add new parameters at the partners request; link to virtual slide repositories and genomic platforms and possibility to enter data directly from standardized reports.
Conclusions: Conticabase is a unique tool for cooperative studies and research. It is also a modern tool with link to specialised databases and it is particularly adapted to rare tumors such as sarcomas.
Category: Bone & Soft Tissue
Monday, March 22, 2010 1:00 PM
Poster Session II # 1, Monday Afternoon