Chronic Hepatitis Feature and Liver Mass in Idiopathic Hypereosinophilic Syndrome – Analysis of Twelve Cases
HJ Lee, SY Choi, YB Kim, MK Yeo, DY Kang. Chungnam National University School of Medicine, Daejeon, Korea
Background: The hypereosinophilic syndrome is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm3) in the peripheral blood for more than six months without evidence for any known causes of eosinophilia and with multisystem organ involvement. Most reported cases of the syndrome were predominant among men and showed chronic hepatitis with the multiple liver masses in radiology.
Design: We analyzed twelve cases of the hypereosinophilic syndrome with chronic hepatitis features in a liver biopsy and a liver mass from 2000 to 2009 at Chungnam National University Hospital.
Results: The cases were ten men and two women, ranging in age from 27 to 66 years (mean, 49.2 years). The clinical presentations of the patients were incidental findings of liver masses (seven cases), fevers (three cases), and abdominal pain or soreness (two cases). The radiologic evaluation showed eight cases with multiple and variable sized lesions, but, in four cases, a single liver mass mimicking malignancy was shown. Most of the cases revealed hypereosinophilia initially, but only one case showed the normal range of eosinophil count initially and was followed by hypereosinophilia.
Conclusions: Our results showed four cases of the idiopathic hypersosinophilic syndrome, which represented a single mass in the liver and a case of normal eosinophil count in initial laboratory tests. All cases showed chronic hepatitis features.
Category: Liver & Pancreas
Monday, March 22, 2010 1:00 PM
Poster Session II # 173, Monday Afternoon