Spectrum of Pathologic Findings in Magnetic Resonance Imaging (MRI)-Guided Breast Core Biopsies
The above table summarizes the rate of malignancy in different groups based on history. The malignancy rate was similar between the group with a history of breast carcinoma and the group without a personal or family history of breast cancer (17.44% vs. 18.75%). Women with a diagnosed breast carcinoma had a higher malignancy rate in the ipsilateral vs. the contralateral breast (11/31 versus 4/38, p=0.013). - Atypical changes were detected in 12/152 cases (7.89%): 9 atypical ductal /lobular hyperplasia (ADH/ALH), 2 ADH bordering on ductal carcinoma in situ (DCIS), and 1 atypical apocrine adenosis. F/U was available in 3 cases. Two ADH bordering on DCIS correlated with DCIS and usual ductal hyperplasia, respectively. One ADH revealed DCIS in subsequent excision. - Benign proliferative changes were detected in 14 cases (9.21%): florid ductal hyperplasia (4), fibroadenoma (7) and papilloma (3). - Nonproliferative fibrocystic changes were detected in 89 cases (58.55%) - Unremarkable breast parenchyma was diagnosed in 15 cases (9.87%).
Conclusions: MRI enhanced breast lesions show a wide spectrum of pathologic findings ranging from invasive carcinoma to unremarkable breast parenchyma. Carcinoma and atypical changes were detected in 22 and 12/152 biopsies, respectively. The remaining 118 cases (77.6 %) were benign.
Wednesday, March 11, 2009 1:00 PM
Poster Session VI # 27, Wednesday Afternoon