[P2.046] Alleviating Maneuvers (Sensory Tricks) in Cervical Dystonia
Neepa Patel,1John Hanfelt,2Laura Marsh,3Joseph Jankovic3
1Dallas, TX, USA, 2Atlanta, GA, USA, 3Houston, TX, USA
Objective: To describe the phenomenology of alleviating maneuvers (AM), also called “sensory tricks” or “geste antagoniste” in cervical dystonia (CD).
Background: There is limited information on the phenomenology, clinical characteristics and pathophysiology of AM in dystonia.
Design/Methods: Subject data, collected from 10 sites participating in the Dystonia Coalition (http://clinicaltrials.gov/show/NCT01373424), included description of localization and phenomenology of AM collected by systematic review of standardized video examinations. Analyses correlated demographic, neurologic, and psychiatric features of CD patients with or without effective AM.
Results: Of 154 subjects studied, 138 (89.6%) used AM, of which 60 (43.4%) reported partial improvement, 55 (39.8%) marked improvement, and 4 (0.03%) no effect on dystonic posture. Light touch, usually to the lower face or neck, was utilized by >90%. The presence or location of AM did not correlate with the severity of the dystonia.
Conclusion: In this large and comprehensive multicenter study of CD we found no clinical predictors of effective AM. Further studies of sensorimotor integration in dystonia are needed to better understand the pathophysiology of AM.
Study Supported by: Office of Rare Diseases Research at the National Center for Advancing Translational Sciences (NIH grant NS 065701) and the Dystonia Medical Research Foundation.
Category - Movement Disorders: Dystonia
Tuesday, April 29, 2014 7:30 AM
P2: Poster Session II: Movement Disorders: Dystonia (7:30 AM-11:00 AM)